Monday morning

8.00 - 10.00Registration, Poster and Exhibitor Set Up and Arrival Refreshments
10.00 - 10.05Conference Welcome Address

In Vitro Models for the Study of Neurological Diseases

TimeSpeakerTalk Title
10.05 - 10.35Keynote:
Professor Geoff Pilkington
University of Portsmouth

3D modelling for chemo sensitivity testing in neurology
10.35 - 10.55Zaynah Maherally
University of Portsmouth
An ‘all human’ 3D in vitro blood brain barrier model in nanoparticles delivery and cancer metastasis studies
10.55 - 11.15Diana Moreira Leite
University of Portsmouth
Towards the Development of a 3D All Human In Vitro Model of Glioblastoma Multiforme for Drug Screening: Glioblastoma and Microglia Interactions?
11.15 - 11.35Jeffrey Bajramovic
Biomedical Primate Research Centre,
The Netherlands
Primary adult microglia: a guided approach towards more relevant in vitro methodology
11.35 - 11.55Emanuel Berger
University of Luxembourg
Millifluidic culture improves human midbrain organoid vitality and differentiation
11.55 - 12.15 Claire Garwood
University of Sheffield
Developing models of impaired insulin signalling in astrocytes and implications for neuronal support
12.15 - 13.30LUNCH

Monday afternoon

Creating More Realistic Gut Models

TimeSpeakerTalk Title
13.30 – 13.50Emma Hernandez-Sanabria
Ghent University
Celecoxib supplementation impacts compositional and functional features of in vitro gut microbial ecosystem
13.50 – 14.10Marta Calatayud
Ghent University
Development of a host microbe interaction in vitro model of the small intestine
14.10 – 14.30Loulou Peisl
University of Luxembourg
immunoHuMiX – an in vitro model to study microbiome-immune system interactions
14.30 – 14.50Andrew Hollins
Cardiff University
Current and future applications for intestinal organoid culture models
14.50 – 15.00Mike Bracher
University of Portsmouth
A Systematic Approach To Review of In vitro models in Brain Tumour Research (SAToRI-BTR)
15.00 - 15.30COFFEE BREAK
15.30 – 16.00
Professor Christophe Lacroix
Institute of Food Science and Nutrition
ETH Zurich

In vitro modelling of colonic fermentation, challenges and solutions
16.00 – 16.20
Lianne Stevens
The Netherlands
InTESTine on-a-chip: Towards a more physiological and predictive human intestinal barrier model
16.20 – 16.40
Stefan Vaessen
University of Applied Sciences Utrecht
Stem cell-derived organoids cultured two-dimensionally: The benefits of organoids with the dosing convenience of epithelial cell lines
16.40 – 17.00
Elena Naumovska
The Netherlands
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes
17.00 - 17.20Jan Markus
Modelling of Live Bacteria or Ligand-Induced Acute and Chronic Inflammation in the Gut using In Vitro 3D-Primary Reconstructed Human Small Intestinal Tissues (EpiIntestinal)
17.20 - 18.00Networking, Poster Viewing, and Exhibitions


Advanced Cell Culture: 3D, Fluid Flow and Co-culture

TimeSpeakerTalk Title
8.30 – 8.50Caroline Taylor,
Manchester Metropolitan University
The assessment of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) for use as an intraluminal guidance scaffold for improving peripheral nerve regeneration using a developed 3D in vitro testing model
8.50 – 9.10
Marta Cavo
A technological approach to recapitulate the breast cancer metastatic model in vitro
9.10 – 9.30
Dania Movia
Trinity College Dublin
3D in vitro models of lung cancer: Understanding the model's characteristics to improve drugs translation 
9.30 – 9.50
Don Wellings
Proliferate - applications in regenerative medicine
9.50 – 10.10
Gary Allenby
Aurelia Bioscience Ltd
Application of novel 3-dimensional electrospun micro-scaffold technology as a drug discovery platform for cell biology
10.10 – 10.30
10.30 – 11.00
Dr Dominic Williams

Novel Human-based Hepatic Safety Models for Mechanistic Risk Assessment: Deployment within the AstraZeneca hepatic safety toolbox
11.00 – 11.20
Elisa Budyn
University of Paris-Saclay
Morphological and physiological changes of osteocytes during bone formating in a bone-on-chip
11.20 – 11.40
Deborah Mason
Cardiff University
3D mechanically-loaded bone cell models for drug screening
11:40 – 12:00
Tamara Zietek
Technical University of Munich
3D intestinal organoids: Functional studies on nutrient uptake, drug bioavailability and gut hormone secretion
Lynne Bingle
University of Sheffield
The development of an organoid model of human salivary glands
12.20 – 12.30
Martin Knight,
Queen Mary University of London 
Organ on a chip network talk
12.30 - 13.30LUNCH
13.30 – 14.00
Dr Murat Cirit

Translational applications of microphysiological systems
14.00 – 14.20
Nikolett Nagy
Upcyte Technologies
Liver bud formation using differentiated human upcyte cells
14.20 – 14.40
Andrew Mearns Spragg
Next generation jellyfish collagen an opportunity for efficient 2D and 3D cell culture applications
14.40 – 15.00
Sandro Meucci
Tailoring the extracellular environment of in vitro systems
15.00 – 15.30
15.30 – 16.00
Dr Paul Walker

Combined in silico and 3D in vitro approaches for the accurate prediction of human drug induced liver injury
16.00 – 16.20
Dominik Egger
University of Natural Resources and Life Sciences,
Dynamic three-dimensional aggregate cultivation for the expansion of mesenchymal stem cells
16.20 – 16.40
Nilofar Faruqui
National Physical Laboratory,
Self-assembled Instructive Extracellular Mimics
16.40 – 17.00
Roeland Hanemaaijer
The Netherlands
Development of a diet-induced disease-mimicking in vitro model of non-alcoholic steatohepatitis (NASH/ fibrosis)
17.00 - 18.00Networking, Poster Viewing, and Exhibitions

Tuesday evening


In Vitro Models for Animal Replacement

TimeSpeakerTalk Title
8.30 - 8.50 Caroline Freathy,
Development of a novel human 3D in vitro model for evaluating new anti-fibrotic drugs
8.50 - 9.10 Jan van der Valk
Utrecht University
The use of foetal bovine serum and its replacement to advance the ethical and scientific quality of in vitro methods
9.10 - 9.30Marieke Hoonakker
Institute for Translational Vaccinology,
The Netherlands
Development of the cAMP reporter assay to replace the in vivo safety test for acellular pertussis vaccines
9.30 - 9.40Anna Maria Bassi
Centro 3R and University of Genova
Towards implementation of the 3Rs in basic research and teaching in Italy: Centro 3R
9.40 - 10.00Taleen Shakouri
University of Hertfordshire
Computational models to predict the binding of small molecules to Cytochrome P450 2D6 to replace the use of animals
10.00 - 10.30COFFEE BREAK
10.30 - 11.00Keynote:
Professor Tommy B Andersson
Novel Microphysiological Multi-Organ Systems for Studies of Human Metabolic Diseases in Drug Discovery
11.00 - 11.20Martin Clift
Swansea University
Advanced in vitro testing strategies to understand the lung cell-(nano)particle interaction at the air-blood barrier
11.20 - 11.40Nirmal Perera
LGC Group,
New advanced in-vitro models developed by ATCC for toxicology and translational cancer research

Stem Cells: Developing off the Shelf Therapeutics

TimeSpeakerTalk Title
11.40 - 12.10Keynote:
Dr Hassan Rashidi

Development of a novel xeno-free protocol to generate phenotypically stable three dimensional hepatospheres from human pluripotent stem cells
12.10 - 12.30Carl Sheridan
University of Liverpool
Seeing is believing in tissue engineering and cell transplants in the eye
12.30 - 12.50 Nick Allen
Cardiff University
IPSC models of neurodegenerative disease
12.50 - 13.10Giorgia Salvagiotto
Cellular Dynamics
Advancing drug discovery and therapeutic programs with physiologically relevant human iPSC-derived cellular systems
13.10 - 13.20Conference close and prize giving
13.20 - 14.30 LUNCH

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