Session Overview

The blood-brain barrier (BBB) is a selectively permeable barrier which separates brain extracellular fluid from circulating blood. It protects the brain from unwanted substances by controlling entry of molecules into the brain.

It is difficult to do large-scale drug screening in vivo to check if new molecules can cross the BBB, and hence there is a need for tissue models. Current tissue models, however, are often unrealistic and difficult to reproduce.

This session welcomes speakers looking to address this need with their research.

Session Chair: Dr Sikha Saha

Associate Professor of Cardiovascular Medicine

University of Leeds

Investigations of novel targets, metabolic profiling, drug delivery, toxicity testing and development of diagnostic tools for cardiovascular and cerebrovascular diseases using novel in vitro organ flow system and in vivo mammalian models

Keynote Speaker: Professor Joan Abbott

PROFESSOR JOAN ABBOTT

EMIRITUS PROFESSOR OF NEUROSCIENCE

KINGS COLLEGE LONDON

 

Title: Building better blood-brain barrier models : Structure, function and value for drug delivery studies

The Presenters

 

Dr Virginia Pensabene

University Academic Fellow

University of Leeds

Title: A novel microfluidic system for growing blood brain barrier cell types

Dr Gary Allenby

Advances in Cell and Tissue Culture - Gary Allenby

CSO and Co-founder

Aurelio Bioscience

Title: The pharmaceutical model is failing – why? 

Dr Stephen Hladky

Emeritus Reader in Membrane Pharmacology

University of Cambridge

Title: Does the blood-brain barrier secrete ISF?

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