Professor of Cellular and Molecular Neuro-Oncology and Head of Brain Tumour Research Centre
(University of Portsmouth)
Paper presenting: 3D modelling for chemo sensitivity testing in neurology
Professor Pilkington has spent his entire career in brain tumour research, having started work on chemical neuro-carcinogenesis where he studied brain cancer stem cells and brain tumour development at the Middlesex Hospital Medical School in the early 1970s and subsequently spent 23 years at the Institute of Psychiatry, King’s College, London, latterly as Professor of Experimental Neuro-oncology.In 2003 he moved to the School of Pharmacy & Biomedical Sciences, University of Portsmouth, as Professor of Cellular & Molecular Neuro-oncology & Director of Research.Over the years the research focus of his group has been development of models for the study of intrinsic brain tumours, elucidation of the mechanisms underlying diffuse local invasive behaviour in glioma, delivery systems for passage of agents across the blood-brain barrier (BBB) and development of novel strategies for mitochondrial mediation of apoptosis in glioma. He has published numerous papers on the results of his research on human glioma and has developed various “all human” three-dimensional in vitro models to study brain tumour invasion and the BBB. At the University of Portsmouth he has established an excellent suite of laboratories and a host of state-of-the-art equipment in which to accommodate the Brain Tumour Research Centre.